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Tesofensine

Triple monoamine reuptake inhibitor studied for appetite regulation. 500mcg and 1mg capsule strengths.

For research use only · not for human consumption

1mg / 30 capsules$100Order at Prime →
500mcg / 30 capsules$50Order at Prime →
View Tesofensine at Prime Bio Group →

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Independent research on Tesofensine. Our sister publication Peptides Uncaged maintains a plain-English research guide covering mechanism, the published literature, and how vendors are scored on purity and COA transparency. It is written independently of any lab. How to read a COA is worth ten minutes before your first order.
The research

What Tesofensine is being studied for

Tesofensine is categorised as a pre-synaptic reuptake inhibitor of dopamine, serotonin and noradrenaline. When these three neurotransmitter chemicals (serotonin, dopamine and noradrenaline) are prevented from being reabsorbed by the central nervous system, the body responds by feeling less hungry. Patients therefore are more inclined to have smaller meals and are less likely to snack.

Tesofensine also appears to affect the pleasure sensation of food consumption by modulating the action of dopamine on a particular sector of the brain. In a double-bind trial with 203 people (with half given a placebo) those taking the placebo had lost 2.0% of body weight while those taking the medication with the active ingredient had experienced far more successful results.

For those taking the lowest dose of 0.25 mg, average weight loss was 6.5%, those taking the medium dose of 0.5mg lost 11.2% and those taking the highest dose of 1 mg lost 12.6%. In the two highest dose groups, the treatment led to a 4 point drop in BMI in a period of 24 weeks. BOTTLE DESIGN MAY VARY TESOFENSINE COA.

Summary of published preclinical and clinical literature, provided for research context only. Not a claim of efficacy and not medical advice.

Common questions

Tesofensine — FAQ

What is Tesofensine?

Triple monoamine reuptake inhibitor studied for appetite regulation. 500mcg and 1mg capsule strengths.

What formats does Tesofensine come in?

Prime Bio Group supplies Tesofensine as capsules. Available options: 1mg / 30 capsules at $100; 500mcg / 30 capsules at $50.

Is there a certificate of analysis for Tesofensine?

Yes. Prime Bio Group is a physician-owned lab and provides a certificate of analysis on every batch. A COA reports identity by mass spectrometry and purity by HPLC — if you are not sure how to read one, our guide on reading a certificate of analysis walks through it line by line.

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