

Triple monoamine reuptake inhibitor studied for appetite regulation. 500mcg and 1mg capsule strengths.
For research use only · not for human consumption
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Tesofensine is categorised as a pre-synaptic reuptake inhibitor of dopamine, serotonin and noradrenaline. When these three neurotransmitter chemicals (serotonin, dopamine and noradrenaline) are prevented from being reabsorbed by the central nervous system, the body responds by feeling less hungry. Patients therefore are more inclined to have smaller meals and are less likely to snack.
Tesofensine also appears to affect the pleasure sensation of food consumption by modulating the action of dopamine on a particular sector of the brain. In a double-bind trial with 203 people (with half given a placebo) those taking the placebo had lost 2.0% of body weight while those taking the medication with the active ingredient had experienced far more successful results.
For those taking the lowest dose of 0.25 mg, average weight loss was 6.5%, those taking the medium dose of 0.5mg lost 11.2% and those taking the highest dose of 1 mg lost 12.6%. In the two highest dose groups, the treatment led to a 4 point drop in BMI in a period of 24 weeks. BOTTLE DESIGN MAY VARY TESOFENSINE COA.
Summary of published preclinical and clinical literature, provided for research context only. Not a claim of efficacy and not medical advice.
Triple monoamine reuptake inhibitor studied for appetite regulation. 500mcg and 1mg capsule strengths.
Prime Bio Group supplies Tesofensine as capsules. Available options: 1mg / 30 capsules at $100; 500mcg / 30 capsules at $50.
Yes. Prime Bio Group is a physician-owned lab and provides a certificate of analysis on every batch. A COA reports identity by mass spectrometry and purity by HPLC — if you are not sure how to read one, our guide on reading a certificate of analysis walks through it line by line.