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Rapamycin

mTOR inhibitor and the single most-studied longevity compound in the literature. 2.5mg and 5mg capsules.

For research use only · not for human consumption

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Rapamycin
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Independent research on Rapamycin. Our sister publication Peptides Uncaged maintains a plain-English research guide covering mechanism, the published literature, and how vendors are scored on purity and COA transparency. It is written independently of any lab. How to read a COA is worth ten minutes before your first order.
The research

What Rapamycin is being studied for

Traditionally Rapamycin was used as a type of anti fungal antibiotic produced by steptomyces hygroscopicus. Currently it is being used in the prevention of transplant rejection because of its immunosuppressive effect. The immunosuppressive effect of Rapamycin is exerted by inhibiting the activation and proliferation of T cells.

Rapamycin binds to FK-binding protein 12 (FKBP12) and forms the Rapamycin-FKBP12 complex, which regulates an enzyme that plays an important role in the progression of the cell cycle. At anti-aging doses, Rapamycin eliminates hyperimmunity rather than suppresses immunity or, more figuratively, it “rejuvenates immunity”. This enables Rapamycin and everolimus, a Rapamycin analog, to act as immunostimulators, improving immunity in cancer patients and the elderly.

For example, rapamycin reduces the risk of CMV infection in organ transplant patients, improves antipathogen and anticancer immunity in mice, prolongs lifespan in infection-prone mice and protects aged mice against pneumonia. Rapamycin also inhibits viral replication. BOTTLE DESIGN MAY VARY RAPAMYCIN (SIROLIMUS) COA.

Summary of published preclinical and clinical literature, provided for research context only. Not a claim of efficacy and not medical advice.

Common questions

Rapamycin — FAQ

What is Rapamycin?

mTOR inhibitor and the single most-studied longevity compound in the literature. 2.5mg and 5mg capsules.

What formats does Rapamycin come in?

ZestyRat Research supplies Rapamycin as capsules. Available options: 2.5mg (30 capsules) at $100; 5mg (30 capsules) at $150.

Is there a certificate of analysis for Rapamycin?

Yes. ZestyRat Research is our top-rated research supplier and provides a certificate of analysis on every batch. A COA reports identity by mass spectrometry and purity by HPLC — if you are not sure how to read one, our guide on reading a certificate of analysis walks through it line by line.

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Our supplier verdict

We rate ZestyRat Research 5 out of 5.

We track pricing, stock and documentation across the research-peptide market every week. ZestyRat is the supplier we point readers to first, and the one our own readers order from most. It is the only lab on our list that clears every one of our four checks at once.

Speed
Order before 3pm ET and it ships the same day. USPS Priority, 2-4 business days.
Testing
Independently tested, 99%+ purity, per ZestyRat's own published standard.
Tracking
Every order ships with tracking. US and Canada. Nothing we have sent has gone astray.
Price
Consistently at or under the market on the compounds researchers buy most.
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Ratings on this page are our own editorial assessment, based on published COA practice, checkout and shipping experience, and price tracking. We earn a commission on orders placed through our links, at no extra cost to you. Research use only.

How we review suppliers

Fresno Peptide Lab is an independent research library. We do not manufacture, stock, price, test or ship anything. We review suppliers on their published testing standards, reputation, fulfilment record and pricing, and the ratings we publish are our own editorial assessment.

Every compound referenced on this site is sold by its vendor strictly as a research chemical for in-vitro laboratory research only — not for human or animal consumption, and not intended to diagnose, treat, cure or prevent any disease. Nothing here is medical advice. We earn a commission on orders placed through our links, at no additional cost to you; all material connections are disclosed in line with FTC guidelines.

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