

AMPK activator studied for endurance and glucose-uptake signaling.
For research use only · not for human consumption
Orders are placed, processed, and shipped by ZestyRat Research. Fresno Peptide Lab does not stock or sell product — we may earn a commission at no extra cost to you.
AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide) is a nucleotide analog and potent AMP-activated protein kinase (AMPK) agonist that plays a critical role in cellular energy homeostasis. By mimicking adenosine monophosphate (AMP) , AICAR activates AMPK pathways, leading to increased glucose uptake, fatty acid oxidation, and mitochondrial biogenesis.
This peptide has been extensively researched for its potential in enhancing endurance, promoting metabolic flexibility, and improving insulin sensitivity. Due to its ability to stimulate ATP production and optimize cellular energy metabolism , AICAR is widely studied in fields such as exercise physiology, metabolic disorders, and cardiovascular health.
Potential applications of AICAR peptide research include: Increased endurance and stamina through enhanced mitochondrial efficiency Improved glucose metabolism and insulin sensitivity for metabolic regulation Enhanced fat oxidation via AMPK-driven energy expenditure Neuroprotective and cardioprotective effects linked to mitochondrial health AICAR continues to be a subject of interest in scientific research for its implications in metabolic regulation, cellular repair, and energy optimization.
AICAR COA.
Summary of published preclinical and clinical literature, provided for research context only. Not a claim of efficacy and not medical advice.
AMPK activator studied for endurance and glucose-uptake signaling.
ZestyRat Research supplies AICAR as vial. Available options: Single unit at $95.
Yes. ZestyRat Research is our top-rated research supplier and provides a certificate of analysis on every batch. A COA reports identity by mass spectrometry and purity by HPLC — if you are not sure how to read one, our guide on reading a certificate of analysis walks through it line by line.
We track pricing, stock and documentation across the research-peptide market every week. ZestyRat is the supplier we point readers to first, and the one our own readers order from most. It is the only lab on our list that clears every one of our four checks at once.
Ratings on this page are our own editorial assessment, based on published COA practice, checkout and shipping experience, and price tracking. We earn a commission on orders placed through our links, at no extra cost to you. Research use only.
Fresno Peptide Lab is an independent research library. We do not manufacture, stock, price, test or ship anything. We review suppliers on their published testing standards, reputation, fulfilment record and pricing, and the ratings we publish are our own editorial assessment.
Every compound referenced on this site is sold by its vendor strictly as a research chemical for in-vitro laboratory research only — not for human or animal consumption, and not intended to diagnose, treat, cure or prevent any disease. Nothing here is medical advice. We earn a commission on orders placed through our links, at no additional cost to you; all material connections are disclosed in line with FTC guidelines.